Indian J Physiol Pharmacol. Oct;45(4) In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves. Singh B(1). Request PDF on ResearchGate | Hepatoprotective activity of Eclipta alba Hassk. against paracetamol induced hepatocellular damage in mice | The effect of. The hepatoprotective activity of different extracts of whole plant Eclipta alba was investigated against CCl4 induced hepatic damage inmale albino rat.

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The hepatoprotective effect of the aqueous extracts of E. Similarly, level of triglyceride, total lipid and cholesterol was found to be decresed after the treatment. Mehra and Handa, This work is licensed under a Creative Commons Attribution 4. On the next day the blood was collected by making an incession by jugular vein to collect the blood. The hepatotoxic agent CCl4 was used to induce liver toxicity and silymarin was used as a control drug.

Total biochemical atcivity was recorded in the present study.

The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4

All hepaoprotective group were given fresh food daily at Animals were kept starved over night on 90 th day. Effects of silymarin nanoemulsion against carbon tetrachloride-induced hepatic damage.

After paraffin embedding block, were stained with Haemotoxylin and Eosin and examined under microscope. Protective effect of picroliv, active constituent of Picrorhiza kurrooa, against oxytetracycline induced hepatic damage. Suresh Kumar and Mishra have also reported hepatoprotective effect of Pergularia demia ethanol extract. They were given a week time to get acclimatized with the laboratory conditions. The protective effect of Eclipta alba on carbon tetrachloride-induced acute liver damage.

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But it was noiticed that the recovery beginning as soon as the plant extract was given. One way analysis of variance ANOVA followed by Scheffes test was applied for determinig the statistical significance of difference in enzymes, protein and lipids levels between different group.

One-way Analysis of Variance was used for the statistical analysis of data. Evaluation of hepatoprotective activity of aqueous extracts of leaves of Basella alba in albino rats. J Biochem Mol Toxicol. Similar results have been observed by Pattanayak and Priyashree which have noticed such changes in the hepatotoxic animal when treated with the extract from Dendrophoe falcanta.

There was a considerable increase in the phospholipids of the plant extract treated group VIth serum as compared to the group 1 which recorded only LP liquid paraffin. The liver tissue was dissected by blotting of the blood washed in saline. A new receipt for liver injury. Antioxidant activity of combined ethanolic extract of Eclipta alba and Piper longum Linn.

Hepatoprotective activity of Cleome viscosa Linn.

The observations of these dose, clearly indicat the involvement of heptoprotective active principles in Eclipta alba. Recent advances in herbal medicine for treatment eclkpta liver diseases.

Development and characterization of phyto-vesicles of wedelolactone for hepatoprotective activity. Keywords Carbon tetrachloride, Hepatoprotective activity, Eclipta alba, Silymarin. Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats. April 04, Published online on: Indian J Exp Biol. Copy the following to cite this article: Drug Dev Ind Pharm. Water was supplied libitum.

This plant acctivity antihepatotoxic activity in assays using CCl4 galactosomine and phalloidin — induced cytotoxicity in cultured rat hepatocytes Wagner et al. Indian J Biochem Biophys.


The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4| Abstract

KSaxena R. As regards the total lipid the value got increased in 50 mg dose but at higher dose, it got decreased which is still much higher then the total lipid values in the control rats.

Hepatoprotective activity of Boerhaavia diffusa L. Rest parameters were found to be all most normal level when three different doges of the compound of the Eclipta alba were given to the CCl4 induced hepatotoxic rat. Hepatoprotective activity of Leptadenia reticulata stems against carbon tetrachloride-induced hepatotoxicity in rats. Twenty four albino rats of wistar albino rats weighing gm were obtained from laboratory hepatoprotsctive college.

In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

Serum was prepared from the collected blood and subjected to biochemical estimation of different parameters like aspartate aminotransferase ASThepaatoprotective aminotransferase ALTalkaline phosphatase ALPtotal lipid, triglceride, phosphatase and cholesterol. Values were little less as compare to the Silymerin. The level of total protein was found to be at normal level after the treatment.

Girish C, Pradhan SC.

The plants were washed thoroughly with tap water and air dried in shade at room temperature. They were fed with pallets of Golden feed, New Delhi.